SELECTED PUBLICATIONS
Roh HC, Tsai LT, Shao M, Tenen D, Shen Y, Kumari M, Lyubetskaya A, Jacobs C, Dawes B, Gupta RK, Rosen ED. Warming induces significant reprogramming of beige, but not brown, adipocyte cellular identity. Cell Metabolism. 2018, 27(5):1121-1137
* Highlighted in F1000Prime, 26 (2018)
Shen Y*, Roh HC*, Kumari M, Rosen ED. Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding. Molecular Metabolism. 2017, 6(10):1150-1160
(*co-first authors)
Roh HC, Tsai LT, Lyubetskaya A, Tenen D, Kumari M, Rosen ED. Simultaneous Transcriptional and Epigenomic Profiling from Specific Cell Types within Heterogeneous Tissues In Vivo. Cell Reports. 2017, 24;18(4):1048-1061
* Highlighted in Nature Methods. 4, 340 (2017)
Warnhoff K, Roh HC, Kocsisova Z, Tan CH, Morrison A, Croswell D, Schneider DL, Kornfeld K. The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc. PLoS Biology. 2017, 17;15(1):e2000094
Roh HC, Dimitrov I, Deshmukh K, Zhao G, Warnhoff K, Cabrera D, Tsai W, Kornfeld K. A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans. Nucleic Acids Research. 2015, 43(2):803-16
Long JZ, Svensson KJ, Tsai L, Zeng X, Roh HC, Kong X, Rao RR, Lou J, Lokurkar I, Baur W, Castellot Jr JJ, Rosen ED, Spiegelman BM. A Smooth Muscle-Like Origin for Beige Adipocytes. Cell Metabolism. 2014, 19(5):810-20
Roh HC, Collier S, Deshmukh K, Guthrie J, Robertson JD, Kornfeld K. ttm-1 Encodes CDF Transporters That Excrete Zinc from Intestinal Cells of C. elegans and Act in a Parallel Negative Feedback Circuit That Promotes Homeostasis. PLoS Genetics. 2013, 9(5): e1003522
Roh HC, Collier S, Guthrie J, Robertson JD, Kornfeld K. Lysosome-Related Organelles in Intestinal Cells are a Zinc Storage Site in C. elegans. Cell Metabolism. 2012, 15(1):88-99
* Highlighted in Nature Chemical Biology. 8, 223 (2012)
Roh HC*, Yoo DY*, Ko SH, Kim YJ, Kim JM. Bacteroides fragilis Enterotoxin Upregulates Intercellular Adhesion Molecule-1 in Endothelial Cells via an Aldose Reductase-, MAPK-, and NF- κB-Dependent Pathway, Leading to Monocyte Adhesion to Endothelial Cells. Journal of Immunology. 2011, 187(4):1931-41 (*co-first authors)
* Highlighted in F1000Prime, 26 (2018)
Shen Y*, Roh HC*, Kumari M, Rosen ED. Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding. Molecular Metabolism. 2017, 6(10):1150-1160
(*co-first authors)
Roh HC, Tsai LT, Lyubetskaya A, Tenen D, Kumari M, Rosen ED. Simultaneous Transcriptional and Epigenomic Profiling from Specific Cell Types within Heterogeneous Tissues In Vivo. Cell Reports. 2017, 24;18(4):1048-1061
* Highlighted in Nature Methods. 4, 340 (2017)
Warnhoff K, Roh HC, Kocsisova Z, Tan CH, Morrison A, Croswell D, Schneider DL, Kornfeld K. The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc. PLoS Biology. 2017, 17;15(1):e2000094
Roh HC, Dimitrov I, Deshmukh K, Zhao G, Warnhoff K, Cabrera D, Tsai W, Kornfeld K. A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans. Nucleic Acids Research. 2015, 43(2):803-16
Long JZ, Svensson KJ, Tsai L, Zeng X, Roh HC, Kong X, Rao RR, Lou J, Lokurkar I, Baur W, Castellot Jr JJ, Rosen ED, Spiegelman BM. A Smooth Muscle-Like Origin for Beige Adipocytes. Cell Metabolism. 2014, 19(5):810-20
Roh HC, Collier S, Deshmukh K, Guthrie J, Robertson JD, Kornfeld K. ttm-1 Encodes CDF Transporters That Excrete Zinc from Intestinal Cells of C. elegans and Act in a Parallel Negative Feedback Circuit That Promotes Homeostasis. PLoS Genetics. 2013, 9(5): e1003522
Roh HC, Collier S, Guthrie J, Robertson JD, Kornfeld K. Lysosome-Related Organelles in Intestinal Cells are a Zinc Storage Site in C. elegans. Cell Metabolism. 2012, 15(1):88-99
* Highlighted in Nature Chemical Biology. 8, 223 (2012)
Roh HC*, Yoo DY*, Ko SH, Kim YJ, Kim JM. Bacteroides fragilis Enterotoxin Upregulates Intercellular Adhesion Molecule-1 in Endothelial Cells via an Aldose Reductase-, MAPK-, and NF- κB-Dependent Pathway, Leading to Monocyte Adhesion to Endothelial Cells. Journal of Immunology. 2011, 187(4):1931-41 (*co-first authors)